Fig. 3
From: Vpr driving DNA methylation variation of CD4 + T cells in HIV-1 infection
Vpr-induced DNA methylation changes mainly distributed in immune-related pathways. (A) The quantity of differentially methylated cytosines (DMCs) specifically induced by Vpr. (B, C) The genomic characteristics of DMCs specifically induced by Vpr on day 3 (B) and day 7 post-infection (C). (D, E) The distribution of DMCs specifically induced by Vpr on each chromosome on day 3 (D) and day 7 post-infection (E). (F, G) The Gene Ontology (GO) enrichment analysis of genes associated with all-hypermethylated (F) or hypomethylated (G) DMCs. (H, I) The GO enrichment analysis of genes associated with promoter-hypermethylated (H) or hypomethylated (I) DMCs.